Okay so, in an adventure on Nessus, Failsafe is reminiscent and mourning one of her crew members. Your ghost sympathizes with her and states,
[quote] "Must have been hard to lose them. I don't know what I would do if...Never mind." [/quote]
It's pretty obvious that he's talking about our guardian permanently dying. But for a guardian to perma die, wouldn't their ghost have to be destroyed?
Most of the ghosts we see that are not destroyed and their guardian is dead are deactivated. So how would our ghost be able to do anything about your death?
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Well if notice many times throughout the lore Ghosts actually have the ability to change Guardians. Not often but it happens. The real question is why are some able to do this? Pull metal and flesh out of thin air, but can’t patch a bullet hole? I think it has more to do with DNA. Each Ghost is specifically coded for particular DNA strand.