Biology will do that a little bit. But Physics will sometimes just shit on everything you know and then smile at you knowingly. :/ For example, gravity hasn't been proven yet because we haven't found the graviton so it's not a fully realised concept... Gravity isn't a fact just a theory! Mind=blown. Science will have you doubt anything and everything. I'm pretty sure electrons, the periodic table and DNA are just some of the things that changed everything for scientists upon discovery.