I use different sets of abilities in PvP versus PvE, and frequently find myself swapping them out at the beginning of that first PvP match of the evening, or after the first time I toss a grenade during the daily heroic and realize I'm still set up for PvP. It would be nice to be able to save (at least) two different profiles for each subclass - one specced out for PvE and one for PvP. This isn't exactly a pressing issue, but it would be nice from a convenience standpoint.