Gears of War 3 [spoiler]When Dom died. That was my favorite trilogy last generation, so seeing one of it's main characters die so late in the series, but not quite at the end of the last game, was a little rough. It was well done, though. Didn't cry. [/spoiler] A close second is The Legend of Zelda: Twilight Princess, [spoiler]When Midna had to go back to the Twilight world at the end of the game, and shattered the mirror with her tear. That one [b]really[/b] got me, I almost cried. She really became one of the best characters in the Zelda series throughout that game, and seeing her part ways like she did just made the feels even worse. [/spoiler]