Who would it be? I would personally pick Wheatley from Portal 2. While kinda a screw-up, he's frickin hilarious.
Edit: Just to clarify, I meant like an artificial intelligence, a machine.
Edit: Cortana seems to be the favorite here (no surprise).
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1 RispondiCortana, only because she's smart and hot(that's a plus).
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1 RispondiIf you dont pick cortana you shouldn't be on these forums
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Clank, from ratchet and clank
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Space, Space space, Im in space