Lsd is the best shrooms is second best out of the list marijuana I don't consider mind altering but I use it to help balance me out. Drugs should be done responsibly and at appropriate times with much time in between use. I personally would suggest doing one of the two once a year or every other year. If you want to do it more frequent at least wait about a month in between use since you release all your brain chemicals at once and on average takes about a month to stabilize them. That's why people who trip every weekend during the summer are usually cranky or at least he trips are not as good as the first of the season.