While fighting the Barricade Mind on Kepler, my game froze and completely crashed after throwing a dusk field nade at it. There were also some harpies next to it when this happened.
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Game crashes during some boss fights. I noticed during the message mission. Every time I kill and explosive shanks during the 2nd phase, I crash. Solution was to not kill the shanks and carefully kill the boss. Now I have the archon. Apparent cause is killing a captain. At least I can use a checkpoint. Running on legendary difficulty.