I don't know what's the most likely, but I don't know much, so tell me what you think
EDIT: ALIENS
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Either; A. Someone will build an army of giant robotic cats that will go rogue, and destroy humanity. B. A weird giant lady will fall from the sky, and afflict everyone with a weird magic disease, and our crazy plan to stop it will fail. C. Some idiot will break Kala’s seal, and then she’ll just hit the reset button. D. Some dude will take a rocket ship from the moon to earth, unknowingly bringing along ome of the top secret human-eating aliens the government was experimenting on on the moon with him.