It's been a few years since bungie vaulted the red war campaign and yet this location still has dialog tied to the red war.
Outside of random seasonal stories, there isn't a solid reason to keep nessus. I mean it's a random backwater planetoid.
If they chose to bring back siva, I could see keeping the destination since exodus black has it on board and they did make a siva variant of the exodus crash. However this likely won't happen since bungie released a blog and mentioned they had no plans for sivas return.
If I was a new player, I'd have little idea what's going on since there is dialog from a character who doesn't exist anymore and there is no real description of what's the vendors deal since that was also tied to the red war.
I feel like the only reason they kept Nessus is because there are 3 strikes and some battlegrounds tied to it, so this would hurt the vanguard ops. Also I believe bungie kept it because it was one of the few Y1 locations that they made and not highnoon or vicarious visions studios as they seemed to have vaulted every location made by those studios.
Personally, I'd like to see them vault nessus (after a quest to plant failsafe in a tower frame, because I know there are a lot of failsafe fans out there) and either replace it with the full leviathan as a patrol zone plus bring back updated versions of the raids/lairs or bring back the dreadnought and strikes tied to it.
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The Vanguard has to figure out how to move Failsafe off of Nessus. She's literally the closest thing to comic relief we have left. R.I.P Cayde.