If you're going to nova bomb the 3 hive majors all the way at the beginning of patrol obviously it's easiest if you can nova bomb them when they're all coming out of the door, but IF YOU GET THERE TOO LATE and they're all already out of the door, then crouch behind the metal crate right in front of the room, turn on the "shatter" perk for your nova bomb so you have 3, and then once they're all kind of grouped together, aim for the middle major's head and you will hit both majors that are on the bottom and the one on top. If they're all on the bottom in that room you can just do the same thing and it'll have the same effect so you will get 7 orbs. I know some people had an issue doing this with the majors since they were already walking around the room so I thought this might help. I did it this way and spawned 7 orbs every time I did this.