For me it is regarding the relic holder during the Atheon fight. The relic holder should give a final cleanse inside the portal when there are still 2 oracles left, then immediately leave the portal and head to the middle tower. This gives everybody outside an extra 5+ seconds of shooting at Atheon during Time's Vengance, while still giving the two guys on oracle duty enough time to kill the final oracles and make it to the relic holder to be cleansed This is such a simple tip, but so few people follow it. Nothing like having the relic holder pop his bubble when Time's Vengance is already down to 20 seconds.