Be sure to get up every couple of hours to do some stretching for about ten minutes to keep the blood circulating properly in your body and to try to prevent blood clots!! No joke on this. The body doesn't do well when it's immobile for long period of time!
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And remember, always follow the instructions in your game manual for a healthier gaming session, such as: 1. Avoid playing if tired or sleep deprived. 2. Make sure that you play in a well-lit room and assure yourself that your screen brightness is well adjusted. 3. When you sit in-front of a screen, make sure you position yourself within a safe viewing distance. 4. Whilst playing the game, do a 10-15 minute break every hour Excerpt, Skyrim(TM) Game manual. MAN-43524