I know there hasn't been confirmation either way yet, but I really hope there is split-screen co-op. I don't particularly enjoy online multiplayer anymore, even thought I probably played 200 hours of Halo 2 and another 200 hours of Halo 3. It's just not my gig like it used to be. I can't get into Borderlands or CoD, I couldn't get into the online multiplayer of Reach or Halo 4. I just don't like playing with/against compressed voices; if I'm going to be alone in the room, I'd rather just play solo.
So here's a +1 hoping Bungie includes split-screen for those of us who enjoy playing games when friends stop over.
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In a game as big as destiny I doubt split-screen will be possible, it's a big enough step making a game this big multiplayer let alone having 2 people per console