I use that same mouse with 0 issues. Do you have the Logitech software loaded at all?
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I used to but removed it just to test if that was causing it...not sure what else to troubleshoot.
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Do you run any macros?
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No. Apparently it's a common issue with G502s of the earlier model line. Stinks but I'll have to replace it. I was able to reproduce the issue on my desktop after some time. Maybe I'll give another mouse a shot for my small hands because I could never reach the precision button anyway.