During the Vault step of Last Wish when picking up the Eye of Riven Relic there is a chance that you can be given a debuff of a plate that has already been cleared. There is also a chance that when clearing a plate with the Relic that it will kill you as if you detonated at the wrong plate, despite the fact that the correct plate was attempted to be cleared. There was a time (this only happened once) that a 2nd Relic spawned after killing and Eye of Riven.