I'm having the same types of issues. I played most of the night last night and then had 1 or 2 hard crashes starting around 1am. This morning I finished up the campaign and probably crashed 2 more times hard, as in, push the power button to restart. Since then it's been crashing continuously. I've reinstalled D2, multiple drivers, multiple times but nothing seems to help. I can crash just in the settings menu adjusting the display. Yesterday I was running at full 2560x1440 max settings with vsync off pushing about 120 fps. I started hitting the crashes earlier so I put vsync on locked at 60fps and still getting crashes, now, when I even turn vsync off it's a hard lock. Are you guys seeing anything in windows event viewer around the time of crash?