None, it'll turn things more tedious.
E.g. lets say that start of a strike you'd prefer a shotty for yellow bars, and in the end a sniper for the boss (getting close is stupid)[spoiler]nerf fusion rifles[/spoiler]
locked loadouts = scout, hc, fusion rifle for everything.
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Use a shotgun for everything, problem solved
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The 'nerf fusion rifle' bit has been beaten to death 100 times over. Let it rest. However I do have something fun for you... [spoiler]muted[/spoiler]