I've Only ever done it from gatekeepers.
Can run relic there and on atheon like a fox! Honestly don't know what's so hard or scary about running relic? I prefer it!!
[spoiler]still never done it from the start or Templar or gorgon lol[/spoiler]
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I like running relic too. Makes things interesting
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Templar is the hardest part as a relic holder