Hyper beam in the original pokemon. I remember playing against friends and that was the only move we used.
M16A3 in battlefield 3.
Can't think of any others that haven't already been mentioned.
Edit 1: oh I remember a couple more.
The famas in Rainbow Six Vegas.
One man army noob tubes in MW2.
English
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Oh ya dawg, I got the tm for it and used the cinnabar island glitch to multiply it, literally a full team of lvl 100 hyper beamers. Too pro.
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I forgot about that glitch hahahaha. Dupping strange candies to max everyone out and fighting that glitched monster.