I would have to say my all time favorite is Eureka 7, followed by Clannad. What's yours?
edit 1: holy crap over 1000 replies! I see we have tons of otakus here. Haha! Keep it up!
-
One Piece got me into the genre about 2 years ago. Sooo One Piece. [spoiler]I prefer the dubbed version instead.. don't crucify me.[/spoiler]