Does it mean that Destiny is a sci-fi or a fantasy game or that Destiny is a blend of these two like Shadowrun?
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Destiny would be a blend. Sci-fantasy includes common fantasy elements fixed with common science fiction elements to create something new. 40k, as ROBERTO mentioned above, takes the classic fantasy races (minus the dwarves) and sticks them in space. Star Wars takes wizardry powers and introduces them to space creating the Jedi. I would expect to see some fantasy race analogues in the game or some form of magic, but that is just me.