If I had read this before playing the FREE game on Steam called Unturned, I would think you are insane. However, Unturned had a leftie option, and it works amazing! My only worry is that I will be so used to my radar being on the left, that I will not be able to swap over. It just adds another layer of personal connection with your characters. Even if all it did was change the left handed players HUD, and have NO EFFECT on what others see, it would be perfectly fine with me.
[spoiler]Left Handers UNITE!![/spoiler]