First off, I am very sorry of this has come up before which I'm sure it has. My question is are any or all missions going to be replayable? Especially since world's will physically be changing with DLC etc. Personally I hope that you can, at least if you create a new character and start again. What do you guys think? Again sorry if this has been covered, I'm not wanting to annoy anyone.
I haven't heard anything about the world physically changing... But, yes, in the podcasts they've talked about going back and taking your friends on your favorite missions to help them score loot.