I wouldn't say it is hand cannons I'd say it's exotic hand cannons. They just have amazing perks on them that makes them lethal. I don't think I've been killed by one red hand, Timurs lash, venation 3, chance, tdyd, or tmph(sp?).
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I killed some people with the lash yesterday
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Fatebringer? I use it when I'm not using thorn or hawkmoon.
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It's not an ideal setup for pvp. I've never been killed with it in crucible.
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Any gun is deadly in the hands of a skilled player. Try Fatebringer with explosive rounds. I wreck all day with it