Mire lurk queen fallout 4. Fought my first one while doing a Minutemen quest and it has an acid spit that almost instantly kills you. Only way I beat it is by getting back far enough out of her range and grabbing a sniper. Went to sneak for the 2x damage multiplier and headshot the hell outta her. Went through 50 sniper rounds. The second was for a quest to follow the freedom trail. You go into some town office or something and fight through more lurks. Then you kill some lobster looking thing. Then you gotta go around highly irradiated areas to turn a switch or a door. Then she spawns out. I quick saved at this point thank god. Then I had to run up a long stair well away from her more lurk lackies. Punch through a crapload of raiders and kill their boss in a powersuit. After I was done with that I rested then took a missile launcher (bosses domain was at the top of this giant chasmwith the queen at the bottom) and unloaded on her from above. Took me 15 missiles