I have one where everytime I spawn in I take radiation damage so I'm gonna have to ditch my level 151 character and several amazing settlements and start afresh.
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Man it sucks. I know how you feel, I lost a level 96 character because my damn files were corrupted
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Yeah I've already lost dogmeat and the super mutant and a lot of the times I try to get into diamond city the whole place bugs out and everyone shoots at me. I'm more leaned towards just leaving game as opposed to restarting until it gets another patch.
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On my very first character I couldn't talk to companions, except for dogmeat which made him the only way to dismiss companions. Super annoying