Not so much getting to me as I just find Shaxx annoying in general. That just happens to be one very specific example.
Also, it would be nice to have presets for regular dialogue and sfx/music between regular play and cinematics etc. in my opinion. During proper cinematics I like to have an emphasis on dialogue with a nice undertone of music and sfx to compliment it, and any possible in game comms turned down to not interrupt, As opposed to during play, where I like to have an emphasis on in game comms (in case being used... 'cept I can't at moment because reasons) followed by SFX with dialogue at a comparable level with the music a bit on the lower end. Having to constantly play with the settings can be a pain, because if I forget to change them back it can get weird. Almost thought I had an audio bug once because I forgot to turn cinematic volume back on at one point and wasn't getting any intro speech during strikes, and then felt like an idiot when I remembered I had cranked it down earlier that day.
So again, it's sort of a preference thing... and there's other stuff this game needs more first for sure, but it is a feature I would personally enjoy.