For me, it's all about the Hand Cannons. I originally loved the Scout rifles, but when you can pop the heads off dregs, Vandals, and Cabal with one trigger pull, the satisfaction is amazing. Sure, reloading sucks, but following up with precision kill after precision kill is why I love PvE. Of all the HCs I have used, I miss my Devil You Know the most. I wish I would have kept her.