I'm not running iCUE on my computer interestingly enough, I have a theory it could be Nvidia trying to "optimize" destiny, but I have ran a dxdiag to see what's going on so hopefully that should help soon.

I have a Gigabyte Aero OC, so I’ve not only reduced it down to normal clock speed for a stock 4090, I’ve also reduced it by another 100 MHz as the Bungie help site suggests. I still got Broccoli errors all night. My dxdiag showed that Destiny is crashing with Live Kernel 141 errors which, according to Microsoft, is related to overclocking. The only things not stock that I did was enable to AMD RAM settings to get my actual memory speeds in the BIOS. I’m at my wits end, I’m about to give up and just move on to bigger and better things.

Honestly, I feel you on that, I'm also getting 141 errors from what I've seen. Hopefully we can find a fix, if not there's always something else to play.