I ran through the specific quest on Nessus where I had to do the specific strike in order to finish the Exotic questline however upon completion I did not advance the questline. No, I did not do the normal strike. I put a marker on the quest itself and followed it until the end. If there is some technicality for what it takes to "complete" the quest I'd be happy to hear it. I did have and use Drang if that was necessary. I killed everything along the way