You don't need to do 100k runs for the rocket launcher. You could literally do 4-6 minute speed runs with arc, heavy weight, and warcliff coil to nuke the boss. I did this consistently with a group for about 3 hours until we all had the gun.
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Thanks for the advice. I am running it since introduction (Warmind DLC). In the past just doing the first run >100k. Afterwards just speedruns as you proposed - it did not help yet.