Honestly, i think they should bring back old modifiers as positive options, like grenadier and brawler. Sometimes you just want to sit back and have fun! Being able to amp difficulty is great, but honestly i miss the old trade-off combos we used to have, like blackout/brawler, or catch/grenadier. Imagine purposefully taking on a -80 Delta difficulty just because you can do an insane amount of ability damage, and still get an upgrade to drop. Not for everyone, or for every run. Just for occasional fun!