Considering said weapon would be rendered useless with Oryx’s demise due to the collapse of his Throne World, I wouldn’t be worried about that.
Thankfully the other two known dangers are already neutralised. Willbreaker’s core was taken by Guardians and turned into three exotic swords, and the tablets of ruin have been rendered obsolete by Quria.
The main threat I see is that the Dreadnaught not only has a massive prison full of Hive, it’s also the perfect hidden staging ground.
Savathûn has the ability to take specifically because of Quria. She taught Quria to use tribute to brute force calculations for her simulations, used this on the simulation of a younger Oryx and learnt the power to Take.