With the help of the protection front the Mother of Creation and the forbidden fruit.
Not because he was actually capable of that being just Spawn.
The Mother of Creation had to grant him God's Power.
So assuming that the case is Spawn (current) vs Venom (current) - then perhaps Spawn would be the winner. But keep in mind that the symbiotic suits attached to both Spawn and Venom are nearly indestructible. And that only Venoms has the capability of morphing into anyone or thing it's has come into contact with (including a liquid mass [host inside]) and also mimics the powers and abilities of said person or thing. i.e. Spider-Man's webbing and Venom's "webbing"