Mine has been in "The Summoning Pits" on Moon, called "The Untamed". Ridiculous health, constant high damage beams and never resting minion waves. It's not impossible, but if you get there low level and no back-up, better say your prayers haha
So, what's your most hated boss nemesis?
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The earth strike was pretty hard in alpha, was basically hard mode version with knights spawning and owning shit despite having full green gear.