Mine has been in "The Summoning Pits" on Moon, called "The Untamed". Ridiculous health, constant high damage beams and never resting minion waves. It's not impossible, but if you get there low level and no back-up, better say your prayers haha
So, what's your most hated boss nemesis?
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Its always been the kill the target public events on mars. But recently I'd have to say Hezen the Hated... That guy just wont go down. Took a full fireteam for me to take him down.