My opinion might be a little bias but I'll go with Skyrim.
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#Offtopic
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Just the enemies we fought in Skyrim? Or all of the ES Universe? LotR has a supreme God, he could meta-physically #rek Elder Scrolls and all of the Deadra. But if we remove magic, I'd say it's a pretty fair fight, though LotR dragons are insane compared to ES dragons...