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I don't understand the question.
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It's just a basic philosophy question: Can we prove anything is real?
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Oh, right. Sorry, you confused me. Well, it depends on how you define real. I would say we can have pretty overwhelming evidence for the tangible existence of something, but I don't think we can know things with absolute objectivity. Things like solipsism and metaphysical nihilism fall away at the feet of empiricism and idealism and rationalism.