Why do you want to know if a ghost can do a gender re-assingment? That's not just the stuff of science fiction, the Mayo Clinic can do it if you pass the psych evaluation and have enough cash. That is a weirdly specific and inane thing to be asking.
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Cuz maybe a guy wants to make a character trans but knows jack all about the medical situation in Destiny and wants to make sure their backstory fits well with the science of fantasy land here. Sure I can SAY yeah this does this so this. But if I have no solid basis in lore then it's no fun. Let me be oddly specific and critical, I'm trying to outsource here.
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Make male/female character. Say it used to be female/male. This is all pretend anyway.
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I'm a writer who likes to get invested in story building for my characters, for me it's not as simple as that lol. I have more fun actually making stuff make sense. And for reference I'm a trans guy... So like, this isn't some cis dude trying to be 'experimental' I'm just trying to write a good background for my Titan.
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Well, kudos to you. Props to you for your openness and no minding a little ribbing.