I just replayed the final mission in the replication chamber 6 times on hard after I did the other 4 missions before it on hard. The final mission is surprisingly short and the bosses can drop exotics, so it was worth the time.
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Oh. So thats how your supposed to do it. Thanks for informing me man.
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It's not a particularly fun way but it was the best/quickest way I could think of and it fulfilled the Book's needs. Best of luck to you, hope you get some exotics