I would have to say my all time favorite is Eureka 7, followed by Clannad. What's yours?
edit 1: holy crap over 1000 replies! I see we have tons of otakus here. Haha! Keep it up!
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2 RepliesEdited by Shadow: 5/30/2015 3:35:07 PM1. Sword Art Online 2. Attack on Titan 3. Irregular at magic school 4. Bleach 5. Fate Zero 6. Hunter X Hunter (can't believe no one said this one yet) 7. Nura: rise of the yokai clan 8. Magi ( No one mentioned this either) 9. RWBY (R.I.P) 10. Death Note 11. Naruto ( let the hate roll in) 12. blue exorcists 13. Digimon ( yes that's an anime) 14. Samurai Champloo 15. street fighter 16. Sekirei 17. noragami 18. Fairy Tale 19. Devil part-timer 20. Black butler 21. Highs school DxD 22. Harlock 23. Soul eater 24. Kill LA Kill 25. Code geass 26. Inyuasha 27. DBZ 28. Zoids (sad its so short) 30. Yu you hakosho 31. Afro Samurai 32. Samurai jack 33. Rosaro + Vampire 34. Squid Girl 35. Hellsing