The RNG perked hand cannons can vary extremely in their usefulness depending on what perks you roll (Timur's lash having the privilege of rerolls) and obviously the "best roll" you can get is subjective and people prefer different perk set ups. So for arguments sake, assume that each RNG perked hand cannon has the optimal possible roll of perks for [u]you[/u]. Let me know what rolls you prefer!
I understand there are other legendary hand cannons but due to space restrictions I only listed the IB, raid and faction hand cannons but if you feel another legendary or even rare hand cannon is better then please comment!
Edit: Maybe I should have put TFWPKY instead of the FWC hand cannon as it seems to be more popular
[spoiler]My favourite is the Red Hand IX[/spoiler]
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Regulator MK 56 w/ luck in the chamber. Same as timur and it's rare