My personal favorites are the Hand Cannon and Scout Rifle.
The Hand Cannon has high impact so shooting from the hip allows for well placed melee strikes. I'll admit that in all other areas I'll go with my trusty Scout Rifle.
The Scout Rifle is my absolute favorite weapon. The high precision firing affords me the opportunity for quicker and more effective headshot kills. The scope, while not quite like the Sniper Rifles, still has distance potential and I find myself sniping targets effectively.
I can't go with anything else at this point, they've become my hunting buddies!