In the Wolves of Mars quest mission "A New Den" Varkis says "Loss of the Queen" that could mean two things: 1)Queen is dead
2)Queen is lost
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She is MIA. Her brother is confirmed alive, and says he can sense her, but she is weak. Per grimoire.
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Orrrr it could just mean that everyone thinks she is dead... If nobody has seen her since the Dreadnaught blew a hole in Saturn's ring, it would be assumed that she is dead. Doesn't mean she is...
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Nope. Dead.