From [url=https://www.facebook.com/BethesdaGameStudios?fref=photo]Bethesda Game Studio's Facebook page[/url], they've given further insight into Fallout 4.
Not only does the game not end after the Main Quest is done, there's no level cap!!!
You can adventure and level, level and adventure for as long as you like!!!
edit = hopefully a better link to proof...
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What specs do I need to run fallout 4 on a laptop?