I couldn't find a recent post with a fix for this, but while I was in the Interference mission, my mouse suddenly stopped moving my camera and I couldn't fire my weapon or use any of the other mouse buttons. I could still use the keyboard to jump and move and bring up menus. I can Alt+Tab out of the game and use my mouse just fine, so it isn't an issue with the mouse. If I open a menu, I can see the mouse cursor and move it around, but I can't click on anything. The only way to fix this seems to be restarting the game, but it is highly inconvenient in the middle of an important mission. I was able to switch to a controller, luckily, and finish the mission, but this seems to be an issue that has been reported many times in the past, but not resolved.