This isn't as hard as it seems guardians. It's actually extremely easy once you figure out what you have to do.
First things first, let's start with classes. The most efficient I've assembled, is two Defender Titans, and a Nightstalker Hunter. Both Titans need to run both Gift of Light, and Gift of the Void simultaneously. One should run weapons, the other blessings. The Hunter should run Light of the Pack, and Black Hole. The idea is to run constant supers.
Now weapons. You're going to need your strongest weapons here guys. Raid weapons would be the best choice since they naturally do more damage to Taken. If you have yet to attempt, let alone complete the raid use the best weapons you have to offer. Snipers/Machine Guns is the best combination for the final boss fight.
Once you board the ketch you're going to want to clear the first two rooms and hallway as fast as possible. Remember, you only have 10 minutes from the time you enter the first room. This should be done within the first 5 minutes maximum. Once you reach the room with the final boss, DO NOT PANIC. Trust your ability and your fireteam and follow my instructions. Upon entering you're all going to want to focus fire on every Blight (black sphere) in the room. These Blights are as spawned basically. Once all are down clear the room of the first wave of ads. After all ads have been cleared do as much damage as quickly as possible to the ultra. Ads will then respawn along with Blights that need to be cleared once again. And from there on its just rinse and repeat. BOTH ADS AND BOSS NEED TO BE ELIMINATED BEFORE THE TIMER RUNS OUT! Use supers when you have them because as long as you are all generating orbs, your super meter should constantly be filled.
Quick Tip: Tethering boss stops him from pitching Nova Bombs at you.
Good luck.
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