T4R
As we all know The Flood are an integral part of the Halo Universe, I was surprised that they weren't featured in Halo 4 to be honest.
When do you think we'll see them?
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I could definitely see them in mid to late Halo 5 so in Halo 6 we know exactly what the enemy will be right away. I'm also assuming we're going back onto Halo now that they discovered the actual location of the other rings. I wouldn't be surprised if the Flood decide to join in again and actually for some reason side with the chief again.