Certain sounds in the game have all of a sudden become muffled: NPC dialogue at the Tower, Jump grunts, Loot Chest Openings. Other certain types of sound work without issue: Music, general sound effects etc. so it's not an issue with my speakers.
I've got a feeling certain audio in the game is stuck at a "menu screen" state, or something similar. I need help, it's really annoying!
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You might have gone to orbit with the low-health muffling in effect. I've repro'd that a couple times myself.