If you could make it almost as overthetop as possible.
I would strap ALOT of fireworks to a zombie, dowse it in gasoline, and throw a lighter at it.
If it came staggering out of the smoke, I would then roundhouse kick its head off.
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How about launching a killer satellite designed for orbital bombardment and unleash it against the infected masses? Boom Boom Boom Boom [b]BOOOM!!![/b](lol It hit the oil refinery :))